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KMID : 1134819990280030613
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Journal of the Korean Society of Food Science and Nutrition
1999 Volume.28 No. 3 p.613 ~ p.618
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Effect of Tea Fungus / Kombucha Beverage on Lipid Metabolism in Streptozotocin - induced Diabetic Male Rats
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Koh Jin-Bog
Choi Mi-Ae
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Abstract
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This study investigated the effect of tea fungus/kombucha(TF) beverage on body weights, pancreas weights, serum glucose and lipid concentrations of both normal and diabetic male rats. Sprague-Dawley male rats weighing 140±10g were randomly assigned to one control and five streptozotocin(STZ)-diabetic groups. Diabetic groups were divided into D-control(TF free water), 20% TFD(20% TF in water), 40% TFD(40% TF in water), 20% TFSD(20% TF disinfection in water) and 40% TFSD(40% TF disinfection in water) according to the level of TF supplementation. Diabetes was experimentally induced by intraperitoneally administration of STZ in citrate buffer(pH4.3) after 3 week feeding of four experimental water. Animals were sacrificed at the 4-week of diabetic state. The diabetic groups showed significant decrease of body weight(-29.4~-48.6g) compared with the control group(72.4g). Pancreatic weights relative to body weights in all diabetic groups were heavier than those of the control group. The levels of fasting serum glucose were higher in all diabetic groups than that of the control group. The concentrations of triglyceride in serum was lower in 20% TFD and 20% TFSD groups than in those D-control group. The levels of total cholesterol, LDL-cholesterol in serum and atherogenic index were significantly decreased in all(20 or 40%) TFD and TFSD groups than in those D-control group, but those were similar to control group. The levels of HDL-cholesterol in serum was similar to all groups, but HDL-cholesterol/total cholesterol ratio were significantly increased in all(20 or 40%) TFD and TFSD groups than in those D-control group. Liver triglyceride concentration of the all diabetic groups significantly decreased compared with the control group. Liver total cholesterol and phospholipid were not affected by TF and TFS feeding. The results indicated that tea fungus/kombucha beverage feeding improved the cholesterol, triglyceride and atherogenic index levels in diabetic rats.
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KEYWORD
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tea fungus/kombucha, blood glucose, lipids, diabetic rats
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